报告题目：Modular and adaptive self-assembling dendrimers for biomedical applications
报告时间：2024年7月26日（星期五），下午2:00
会 场：中国药科大学江宁校区新实验大楼一期121
报 告 人：彭 玲 研究员
主 持 人：刘潇璇 教 授
报告人简介：
Dr. Ling Peng is currently a research director of exceptional class at the Interdisciplinary Center on Nanoscience in Marseille (CINaM), which is a part of the French National Scientific Research Center (CNRS). She is working actively at the interface of chemistry and biology. Notably, she has inaugurated the concept of self-assembling supramolecular dendrimers, which have inspired and transformed the field of dendrimer science for biomedical applications in drug delivery, gene therapy and biomedical imaging.
Dr. Peng is the Distinguished Member of the French Chemical Society, and was honored with the Prize of Dr & Mme Henri Labbé by the French Academy of Sciences in 2017, the Grand Prize of the French Chemical Society SUD PACA and the André Collet Prize of Supramolecular Chemistry by the French Chemical Society in 2024.
报告摘要：
The application of nanotechnology is widely expected to bring breakthrough in medicine for disease treatment and diagnosis. Dendrimers are ideal precision materials for elaborating nanomedicine by virtue of their well-defined structure, multivalent cooperativity and nanosize per se. We have pioneered modular and adaptive self-assembling dendrimer nanosystems for biomedical applications such as the delivery of anticancer drugs, nucleic acid therapeutics and imaging agents for cancer detection and treatment. Remarkably, these supramolecular dendrimer nanosystems are able to exploit the in situ tumor-secreted extracellular vesicles for effective delivery and deep penetration in tumor tissue, while overcoming tumor heterogeneity and dynamic evolution. Our findings offer a fresh perspective for exploiting the advantageous features of dendrimer nanomaterials to reach the ultimate goal of nanomedicine.
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高端药物制剂与材料研究中心
2024年7月18日
